There are two clinical forms: bullousand common. The common type is rarely biopsied. The bullous form of impetigo shows a subcorneal bulla with a dermal inflammatory response (figure 1). There are acantholytic cells in the superficial epidermis accompanying degenerated keratinocytes and small … See more Impetigo is a common superficial bacterial infection of the skin. Streptococcus and/or Staphylococcus species are the usual causative organisms. See more Gram stain may be helpful to demonstrate the organisms. Correlation with cultureresults can sometimes be helpful. See more Staphylococcal scalded skin syndrome — also exhibits a subcorneal bulla with acantholytic cells. The inflammatory response in the dermisand superficial neutrophils are typically absent. Pemphigus … See more WebEarly acantholytic bullae are followed by epithelial hyperplasia and intraepithelial abscess formation. These pustular “vegetations” contain abundant eosinophils and can have a verrucous appearance. Pemphigus vegetans–type lesions may also be seen during a lull in the general course of pemphigus vulgaris. Spontaneous remission may occur ...
Bullous diseases - Libre Pathology
WebAcantholysis Occurs in all forms of Pemphigus Desmosome s (intracellular bridges) disrupted Results in loss of Keratinocyte cohesion Acatholytic cells become … WebAcantholytic subset. Acantholysis, with little or no dyskeratosis, can be seen as an incidental phenomenon 1009 or as a solitary tumor of the skin – acantholytic acanthoma ... The suprabasal bulla frequently contains chronic and acute inflammatory cells, including eosinophils. The presence of eosinophils in oral vesiculoulcerative lesions is ... koppers treated lumber
Autoimmune blistering diseases: Histologic meaning
WebPemphigus vulgaris is an autoimmune intraepidermal bullous disease that presents with suprabasal acantholysis (Figure 3). 2 The epidermis is not thickened and acantholysis is … WebDec 14, 2016 · The bulla over the scrotum ruptured to reveal frank superficial erosion (Fig. 2 ). Examination of oral mucosa revealed ill-defined erosions and hemorrhagic crusts. Genital, ocular, and nasal mucosae were not involved. There was no involvement of palms and soles. Systemic examination was normal. WebMay 1, 2002 · Bullous pemphigoid is an autoimmune skin disorder characterized by subepidermal blistering that results in large, tense bullae. It occurs mainly in the elderly … m and co receivership