Cimetidine and theophylline drug interaction
WebThis interaction may be worse if you have heart failure, liver disease, kidney disease, or are on large doses of a theophylline derivative.Your healthcare professionals may already be aware of ... Webdrug interactions checker cimetidine oral and theophylline oral interactions. cimetidine oral brand names and other generic formulations include: Acid Reducer (cimetidine) Oral, …
Cimetidine and theophylline drug interaction
Did you know?
WebDrug Interactions Cytochrome P450 Inhibition Strong and Moderate Inhibitors of CYP3A4 or CYP2D6 The effects of ketoconazole (a strong inhibitor of CYP3A4) at 400 mg once daily for 5 days on the pharmacokinetics of a single tamsulosin hydrochloride capsule 0.4 mg dose was investigated in 24 healthy volunteers (age range 23 to 47 years). WebIn summary, cimetidine is a potent inhibitor of liver microsomal activity, which may also decrease hepatic blood flow. Other effects of the drug include inhibition of gastric secretion and intrinsic toxic properties. These effects, combined with the common use of cimetidine in clinical practice, make the risk of adverse drug interactions a ...
WebDrug Interactions: What You Need to Know By Evan Starkman Medically Reviewed by Joshua Conrad, PharmD What Are Drug Interactions? What Are the 3 Types of Drug … WebThe tablet drug load (10.5–19.5 mg) of theophylline (2.25 mg increments) and cimetidine (3 mg increments) could easily be differentiated using univariate analyses.
WebTheophylline is used to treat lung diseases such as asthma and COPD ( bronchitis, emphysema ). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a ... WebCimetidine, 1,200 mg/day, significantly decreased theophylline clearance by 36% (range, 22% to 49%) and increased the mean elimination half-life from 5.7 hours …
Webcimetidine theophylline. Applies to: cimetidine and theophylline. Using theophylline together with cimetidine may increase the effects of theophylline. Contact your doctor if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, …
WebDec 13, 2012 · Clinically important interactions are predominantly manifested in those drugs which have a narrow therapeutic index (e.g. Phenytoin, warfarin, theophylline). The interaction leads to higher steady-state blood concentrations and hence increases the incidence of side effects and toxicity. Adverse effects of such interactions can be … church media tv monaghanWebApr 1, 2024 · However, children younger than 1 year of age are more likely to have serious side effects, which may require caution and an adjustment in the dose for patients receiving theophylline. Geriatric . Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of theophylline in the elderly. church media tv melmountWebTheophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a solution (liquid) to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. dewalt cordless paint sprayer ukWebAug 25, 2024 · Severe interactions of cimetidine include: astemizole; cisapride; dofetilide; eliglustat; lomitapide; pimozide; terfenadine; Cimetidine has serious interactions with at … church media tv st monicas bootleWebInfluences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. Group Y consisted of nine young adults, aged 22–35 years, and Group O of nine elderly adults, aged 60–74 years. Each subject completed three study phases in this randomized crossover study. During Phase A, oral dosing of 5 mg/kg theophylline was ... church medical cabinetWebAfter intravenous administration of cimetidine, the majority of the parent drug (58-77%) is eliminated unchanged in the urine. 2,7 Cimetidine’s primary metabolite is cimetidine sulfoxide and represents an estimated … dewalt cordless pancake air compressorWebApr 22, 2024 · Adult dosage (ages 18–59 years) The usual starting dose is 300–400 mg per day. After 3 days, your dose may be increased to 400–600 mg per day if you don’t have any side effects. After 3 ... church media tv parish of carndonagh