WebDHX9 has also been shown to directly interact with CBP to aid in recruitment of RNA polymerase II to CRE-containing genes, 46 with the ATPase activity of DHX9 being important for transcriptional induction of genes regulated by a CRE sequence. 47 These data prompted us to test if Nup98 could stimulate CBP-dependent transcription in a … WebMar 6, 2024 · ATPase Assays. One of the most robust uses of measuring ATPase inhibition is with an ATPase Activity Assay. The protocol developed by BellBrook Labs has been in use for over ten years, with …
ATPase Assay Kit (Colorimetric) (ab234055) Abcam
WebThe RNA helicase DHX9 is an ATP-dependent DExH box helicase that can unwind DNA and RNA. Much evidence has implicated DHX9 at multiple levels of gene expr WebDHX9 is part of cluster 34 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore … great lakes pay specific loan
Establishment of a Primary Screening Assay for the DHX9 Helicase ...
WebMar 5, 2024 · DExD/H-box RNA helicases (DDX/DHX) are encoded by a large paralogous gene family; in a subset of these human helicase genes, pathogenic variation causes neurodevelopmental disorder (NDD) traits and cancer. DHX9 encodes a BRCA1-interacting nuclear helicase regulating transcription, R-loops, and homologous recombination and … WebCompare DHX9 Kits from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more. WebAug 1, 2012 · The goal of this project is to develop HTS assays that will allow discovery of small molecule inhibitors of DHX9, which in turn, can be used in cell and animal models to examine the consequences of inhibition of this protein on cancer cell survival. ... Pelletier, Jerry (2015) Establishment of a Primary Screening Assay for the DHX9 Helicase ... great lakes pediatrics