WebMar 1, 2024 · Figure 1. Organization of axonemal dynein motors. (A) Linear map of a generic ∼4500-residue dynein heavy chain.The amino-terminal region contains two conserved segments found in nearly all these motors: DHC_N1 is involved in heavy-chain assembly, whereas DHC_N2 represents the linker that traverses the plane of the AAA … WebOct 31, 2005 · Cytoplasmic dynein is the major microtubule minus end–directed motor protein of the cell; it is involved in many essential cellular processes such as membrane trafficking and mitosis. The cytoplasmic dynein complex is resolved on SDS–polyacrylamide gels into subunit polypeptides of ∼530 (dynein heavy chains), ∼74 (intermediate chains ...
Structure of a microtubule-bound axonemal dynein
WebAll lanes : Anti-Dynein axonemal intermediate chain antibody [EPR11222-78] (ab169758) at 1/1000 dilution Lane 1 : Human Fetal brain lysate Lane 2 : Human hypothalamus lysate Lysates/proteins at 10 µg per lane. Predicted band size: 73 kDa. WebJan 20, 2024 · Structure of a microtubule-bound axonemal dynein Nat Commun. 2024 Jan 20;12(1):477. doi: 10.1038/s41467-020-20735-7. ... intermediate and light chain subunits, and provides a framework to understand the roles of individual subunits and the interactions between dyneins during ciliary waveform generation. craig walk bowness on windermere
Q9C0G6 - UniProt
WebJun 1, 2006 · Dynein axonemal light intermediate chain 1 ( dnali1 ) is an important part of axonemal dyneins and plays an important role in the growth and development of animals. However, there is little ... WebCoordinated movement of the dynein arms causes the entire axoneme to bend back and forth. IDAs and ODAs have different combinations of protein components (subunits) that … Web1 day ago · Outer dynein arms in the ciliary axoneme generate force for ciliary beating. Here, cryo-electron tomography study of the outer dynein arm from the unicellular alga C. reinhardtii revealed structures of multiple intermediate and prepower stroke states in the presence of ATP, as well as structural differences between in situ and in vitro … craig walker hockey