Mycothiol 中文
WebAbstract. The synthesis of a simplified thioglycosidic analogue ( 2) of mycothiol ( 1) is described. Evaluation of 2 against mycothiol S-conjugate amidase from Mycobacterium tuberculosis reveals good specific activity (7500 nmol min -1 mg-protein -1, vs 14 200 for 1), indicating that 2 can serve as a starting point for antitubercular drug design. WebMycothiol C17H30N2O12S CID 441148 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...
Mycothiol 中文
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WebBuy Mycothiol (CAS No. 192126-76-4) from Smolecule. Purity: >98% (or refer to the Certificate of Analysis).Molecular Formula: C17H30N2O12S. Molecular Weight: 486.5 g/mol. Mycothiol is a pseudodisaccharide, 1D-myo-inosityl-alpha-D-glucopyranoside, in which the hydroxy group at the 2-position of the glucose moiety is replaced by an (N-acetyl-L … Web(NT103) Die Anwendung des Mittels muss in einer Breite von mindestens 20 m zu angrenzenden Flächen (ausgenommen landwirtschaftlich oder gärtnerisch genutzte Flächen, Straßen, Wege und Plätze) mit einem verlustmindernden Gerät erfolgen, das in das Verzeichnis "Verlustmindernde Geräte" vom 14.Oktober 1993 (Bundesanzeiger Nr. …
WebThe pseudodisaccharide mycothiol is present in millimolar levels as the dominant thiol in most species of Actinomycetales . The primary role of mycothiol is to maintain the intracellular redox homeostasis. As such, it acts as an electron acceptor/donor and serves as a cofactor in detoxification reactions for alkylating agents, free radicals and ... WebDescription: Mycothiol is a glyco-inositol-cysteine that conjugates exogenous compounds for detoxication. It is the microbe equivalent of glutathione in the eukaryote, and is acted on by mycothiol disulfide reductase and mycothiol S-conjugate amidase and MDF dehydrogenase.
WebAbstract: Mycothiol is the major low-molecular-mass thiol in M. tuberculosis, which plays an important role in maintaining redox homeostasis. Mycothiol acetyltransferase (MshD) finishes the... Web30 jan. 2014 · Author Summary Approximately 30% of the global population is infected with Mycobacterium tuberculosis (Mtb). Persistence of Mtb in host phagocytes depends on its ability to resist oxidant-mediated antibacterial responses. Mycothiol (MSH) is the main antioxidant that provides an abundant source of reducing equivalent, which protects Mtb …
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WebMycothiol is the predominant thiol in most actinomycetes, including Mycobacterium tuberculosis, and appears to play a role analogous to glutathione, which is not found in these bacteria. The enzymes involved in mycothiol biosynthesis are of interest as potential targets for new drugs directed against tuberculosis. In this work we describe the isolation … chema\u0027s trucking llcWeb人 类 所 患 的 多 类 疾 病 均 与 某 些 霉 菌 毒 素 有 关 。. T he mycotoxins foun d to occur significantly in naturally contaminated foods and feeds include the aflatoxins, ochratoxin … flickplay appWeb21 jan. 2015 · 林可霉素是一种含有硫元素的抗感染抗生素,已长达半个多世纪被广泛用于对盘尼西林(青霉素)类抗生素敏感的细菌感染患者的临床治疗。 然而,如此重要的药 … chemawa golf clubWeb16 aug. 2010 · Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes (2008) Vishnu Karthik Jothivasan et al. NATURAL PRODUCT REPORTS Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages chemawa indian health center dentalWebマイコチオール (mycothiol, MSH or AcCys-GlcN-Ins)は、 放線菌 で見られる珍しい チオール である [1] 。 アミノ基 が アセチル化 された システイン と グルコサミン 、 イノシトール から構成される化合物である [2] 。 酸化体であるジスルフィド型(MSSM)はミコチオン(mycothione)よ呼ばれ、 フラボタンパク質 ミコチオンレダクターゼ によっ … flickplayWeb1 nov. 2006 · Mycothiol is the major low-molecular-weight thiol found in actinomycetes, including Mycobacterium tuberculosis, and has important antioxidant and detoxification functions. Gene disruption studies have shown that mycothiol is essential for the growth of M. tuberculosis. chemawa indian health center salem orWeb23 dec. 2010 · Mycothiol (MSH) was prepared according to the procedures described previously (Feng et al. 2006 ). Table 1 Bacterial strains, plasmids, and primers used in this study Full size table Cloning of gentisate degradation genes and sequence analyses flickplay coin